- (White-blooded) The crocodile icefish or white-blooded fish (Channichthyidae) are a family of perciform fish found in the cold waters around Antarctica and southern South America. Fifteen species of crocodile icefish are known. They feed on krill, copepods, and other fish.
white blood
- A small room in which a prisoner is locked up or in which a monk or nun sleeps
- (cell) any small compartment; “the cells of a honeycomb”
- A small compartment in a larger structure such as a honeycomb
- (cell) a device that delivers an electric current as the result of a chemical reaction
- A small monastery or nunnery dependent on a larger one
- (cell) (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
cells
- Of great vertical extent
- at a great altitude; “he climbed high on the ladder”
- a lofty level or position or degree; “summer temperatures reached an all-time high”
- Far above ground, sea level, or another point of reference
- greater than normal in degree or intensity or amount; “a high temperature”; “a high price”; “the high point of his career”; “high risks”; “has high hopes”; “the river is high”; “he has a high opinion of himself”
- (after a measurement and in questions) Measuring a specified distance from top to bottom
high
high white blood cells – GSTM1 null
Description:
The influence of the genetic deletion polymorphism of glutathione S-transferase @m 1 (GSTM1^*0/^*0) on levels of anti (+/-)-r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (anti-BPDE-DNA) adduct in the peripheral blood lymphocyte plus monocyte fraction (LMF) of coke-oven workers was investigated. A total of 95 male Polish coke-oven workers (60% current smokers) from two different plants comprised the sample population. Polycyclic aromatic hydrocarbons (PAH) exposure was assessed by means of the individual post-shift urinary excretion of 1-pyrenol (mean+/-S.D.: 6.93+/-7.20@mmol/mol creatinine; 70% of the subjects exceeded the proposed biological exposure index (BEI) 2.28@mmol/mol creatinine). Anti-BPDE-DNA adduct levels were detected by high performance liquid chromatography (HPLC)/fluorescence analysis of the anti-BPDE tetrol I-1 released after acid hydrolysis of DNA samples. Genotypes were determined by polymerase chain reaction (PCR) on the genomic DNA of each subject. Coke-oven workers without active GSTM1 (GSTM1^*0/^*0, 33%) had significantly higher adduct levels than those with active GSTM1 (GSTM1^*1/^*1 and ^*1/^*0) (5.90+/-5.59 versus 3.25+/-2.01 adducts/10^8 bases, Mann-Whitney U-test, z=2.53, P=0.011), PAH exposure in the two subgroups being similar (7.06+/-6.83 versus 6.67+/-8.00 1-pyrenol @mmol/mol creatinine). The highest number of GSTM1 null subjects (12/23, 39%) belonged to the quartile with the highest adduct levels (i.e., >4.67 adducts/10^8 nucleotides). That is, coke-oven workers with GSTM1^*0/^*0 genotype had a significantly higher risk of having high adduct levels than individuals with active GSTM1 genotype (Fisher exact test P=0.0355; odds ratio (OR)=4.145, 95% CI 1.0-18.8). Multiple linear regression analysis showed that the increase in anti-BPDE-DNA adduct levels in LMF was significantly related to the high occupational exposure to PAHs (benzo[a]pyrene (BaP)) of coke-oven workers (t=3.087, P<0.01) and to the lack of GSTM1 activity (t=3.512, P<0.001), rather than to the two other confounding factors of PAH intake, i.e. charcoal-broiled meat consumption and smoking habits. In conclusion, our results indicate the clear influence of the GSTM1 detoxifying genotype on anti-BPDE-DNA adduct formation in the LMF of coke-oven workers. This is invaluable for future environmental-occupational studies using this biomarker of PAH exposure.
Day 24: The Smallest Universe
This is part of me, after all. This is my blood, under a high powered microscope.
I went to my blood doctor, a naturopath, today. This was only my second time going ever and it was just as fascinating as it was the first time. My blood is super clean and awesome this time around, minus a few other things that are in my alternate shots for the day in my photo stream.
The little Os are red blood cells. They look good- they’re perfectly round, strong, and smooth. If they had dark spots, holes, or jagged edges it would be a bad thing and you’d be able to see it. In the past, my red blood cells looked like little targets with dark centers because I wasn’t breathing deeply enough and they were under-oxygenated.
The white glowy thing that kinda looks like a smiley face is a white blood cell. There should only be a dozen or so in one drop of blood, which is all the sample requires. Again, this guy is super healthy. He is smiling, after all.
I’ve said more about other stuff in the other pictures I uploaded and the notes I left on each photo.
I hope you’re as fascinated as I am. Feel free to ask any questions in the comments- I’ll try to answer.
Granulocyte and red blood cells
high white blood cells
HIGH WHITE BLOOD CELLS 